Properties and Preparation: Sodium carboxymethyl cellulose (CMC-Na) is an organic compound with the chemical formula [C6H7O2(OH)2OCH2COONa]n. It is a carboxymethylated derivative of cellulose and is the most common ionic cellulose gum. Sodium carboxymethyl cellulose is usually an anionic polymer obtained by reacting natural cellulose with caustic alkali and monochloroacetic acid. Its molecular weight ranges from several thousand to millions. CMC-Na is a white fibrous or granular powder that is odorless, tasteless, and hygroscopic, and it disperses easily in water to form a transparent colloidal solution.
Application areas: Widely used in solid preparations, such as capsules, solid granules, tablets, and coating premixes; it can also be used in semi-solid and liquid preparations.
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